Generic Name: belladonna and opium (rectal) (BEL a DON a and OH pee um)
Brand Names: B & O Supprettes 15-A, B & O Supprettes 16-A
What is belladonna and opium?
Belladonna is a natural substance made from a toxic plant. The medicinal form of belladonna has many effects in the body, such as decreasing muscle activity.
Opium is also a natural substance made from the seeds of a plant. The medicinal form of opium is a narcotic pain reliever.
The combination of belladonna and opium is used to treat moderate to severe pain caused by muscle spasms in the tubes that connect the kidneys to the bladder.
Belladonna and opium may also be used for purposes not listed in this medication guide.
What is the most important information I should know about belladonna and opium?
Do not take belladonna and opium rectal by mouth. It is for use only in your rectum. You should not use belladonna and opium if you have glaucoma, a muscle disorder, severe breathing problems, diarrhea caused by infection, severe liver or kidney disease, seizures, severe bleeding, a history of head injury, if you are debilitated, or if you have recently used drugs or alcohol. There are many other drugs that should not be used together with belladonna and opium rectal. Tell your doctor about all other medicines you use.
Before using belladonna and opium, tell your doctor about all of your medical conditions.
Opium may be habit-forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
What should I discuss with my health care provider before using B & O Supprettes 16-A (belladonna and opium (rectal))?
Do not use belladonna and opium if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) within the past 14 days.
Do not use belladonna and opium if you are also using linezolid (Zyvox), pramlintide (Symlin), procarbazine (Matulane), naltrexone (ReVia), or potassium supplement tablets or capsules.
You should not use this medication if you are allergic to belladonna or opium, or if you have:
glaucoma;
urination problems or an enlarged prostate;
severe liver or kidney disease;
a blockage in your stomach or intestines;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
diarrhea caused by infection;
severe bleeding;
a muscle disorder such as myasthenia gravis;
asthma or severe breathing disorder;
if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications; or
if you are bed-ridden or otherwise debilitated.
To make sure you can safely use belladonna and opium, tell your doctor if you have any of these other conditions:
liver or kidney disease;
heart disease, high or low blood pressure;
a stomach or intestinal disorder;
chronic obstructive pulmonary disease (COPD) or other breathing problems;
depression or mental illness;
curvature of the spine;
gallbladder disease;
Addison's disease or other adrenal gland disorders;
underactive thyroid;
drug or alcohol addiction; or
an allergy to atropine or any narcotic pain medicine such as hydrocodone (Lortab, Vicodin), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (OxyContin), and others.
FDA pregnancy category C. It is not known whether belladonna and opium will harm an unborn baby. Opium may cause addiction or withdrawal symptoms in a newborn if the mother uses the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether belladonna and opium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Opium may be habit-forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
How should I use B & O Supprettes 16-A (belladonna and opium (rectal))?
Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Do not take a belladonna and opium rectal suppository by mouth. It is for use only in your rectum. Wash your hands before and after inserting the rectal suppository.
Try to empty your bowel and bladder just before using the belladonna and opium suppository.
Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.
Lie on your back with your knees up toward your chest. Gently insert the suppository into your rectum about 1 inch.
For best results, stay lying down after inserting the suppository and hold it in your rectum for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom for at least an hour after using the suppository.
Drink plenty of water to prevent constipation while using belladonna and opium.
Belladonna and opium rectal is most often used 1 or 2 times per day. Do not use the suppositories more than 4 times per day. Follow your doctor's instructions. Call your doctor if your symptoms do not improve, or if they get worse while using this medication.
Do not stop using the medication suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when you stop using belladonna and opium rectal. Store at room temperature away from moisture, heat, and light. Do not refrigerate or freeze the suppositories. Ask your pharmacist how to properly dispose of any unused suppositories that are no longer needed. Keep track of the amount of medicine used from each new supply of this medication. Opium is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
What happens if I miss a dose?
Since belladonna and opium is used on an as needed basis, you are not likely to miss a dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include feeling restless or excited, confusion or unusual behavior, muscle weakness, weak or shallow breathing, fainting, or coma.
What should I avoid while using belladonna and opium?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid becoming overheated or dehydrated during exercise and in hot weather. This medication can decrease sweating and you may be more prone to heat stroke.
Drinking alcohol can increase certain side effects of belladonna and opium.
Belladonna and opium side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
painful or difficult urination;
urinating less than usual or not at all;
fast heart rate;
weak, shallow breathing;
extreme weakness, feeling like you might pass out;
headache, confusion; or
severe constipation and stomach pain.
Less serious side effects may include:
drowsiness, dizziness;
blurred vision;
nausea, vomiting, constipation;
dry mouth, dry eyes;
decreased sense of taste; or
impotence, loss of interest in sex, or trouble having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect belladonna and opium?
Many drugs can interact with belladonna and opium. Below is just a partial list. Tell your doctor if you are using:
a blood thinner such as warfarin (Coumadin);
cimetidine (Tagamet);
rifampin (Rifadin, Rifater, Rifamate);
cold or allergy medicines;
an antidepressant such as amitriptyline (Elavil, Etrafon), nortriptyline (Pamelor), trazodone (Desyrel), and others;
medicine to treat a mental illness, such as clozapine (Clozaril, FazaClo), chlorpromazine (Thorazine), and others;
diazepam (Valium) or similar medicines such as alprazolam (Xanax), clorazepate (Tranxene), lorazepam (Ativan), midazolam (Versed), temazepam (Restoril), triazolam (Halcion), and others;
a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others; or
narcotic medicine such as fentanyl (Actiq, Duragesic), hydrocodone (Lortab, Vicodin, Vicoprofen), methadone (Dolophine, Methadose), morphine (Avinza, Kadian, MS Contin, Oramorph), oxycodone (OxyContin, Percocet, Combunox), and others.
This list is not complete and other drugs may interact with belladonna and opium. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More B & O Supprettes 16-A resources
- B & O Supprettes 16-A Side Effects (in more detail)
- B & O Supprettes 16-A Use in Pregnancy & Breastfeeding
- B & O Supprettes 16-A Drug Interactions
- B & O Supprettes 16-A Support Group
- 2 Reviews for B & O Supprettes6-A - Add your own review/rating
Compare B & O Supprettes 16-A with other medications
- Overactive Bladder
Where can I get more information?
- Your pharmacist can provide more information about belladonna and opium rectal.
See also: B & O Supprettes6-A side effects (in more detail)
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