Beyaz

Generic Name: drospirenone, ethinyl estradiol, and levomefolate (Oral route)

droe-SPYE-re-none, ETH-i-nil es-tra-DYE-ol, lee-voe-me-FOE-late KAL-see-um, lee-voe-me-FOE-late KAL-see-um

Oral route(Tablet)

Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs should not be used by women who are over 35 years of age and smoke .

Commonly used brand name(s)

In the U.S.

• Beyaz


• Safyral

Available Dosage Forms:

• Tablet

Uses For Beyaz

Drospirenone, ethinyl estradiol, and levomefolate combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and drospirenone, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented.

This medicine is also used to treat premenstrual dysphoric disorder (PMDD) and acne in women at least 14 years of age. PMDD is a severe form of premenstrual syndrome (PMS). Patients with PMDD may have severe emotional and physical symptoms a few days before their menstrual flow starts.

This medicine also contains levomefolate, which is a form of folic acid. Folic acid is one of the B vitamins that pregnant women need to help prevent neural tube defects in a baby.

No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.

This medicine does not prevent AIDS or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.

This medicine is available only with your doctor's prescription.

Before Using Beyaz

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies on the relationship of age to the effects of drospirenone, ethinyl estradiol, and levomefolate combination have not been performed in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medication in teenagers are not expected. This medicine may be used for birth control in teenage females but should not be used before the start of menstruation.

Geriatric

Appropriate studies on the relationship of age to the effects of drospirenone, ethinyl estradiol, and levomefolate combination have not been performed in the geriatric population. This medicine should not be used in elderly women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Boceprevir

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Boceprevir


• Felbamate


• Isotretinoin


• Paclitaxel


• Paclitaxel Protein-Bound


• Theophylline


• Tizanidine


• Tranexamic Acid

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alprazolam


• Amoxicillin


• Ampicillin


• Amprenavir


• Aprepitant


• Atazanavir


• Bacampicillin


• Betamethasone


• Bexarotene


• Bosentan


• Carbamazepine


• Colesevelam


• Cyclosporine


• Darunavir


• Delavirdine


• Doxycycline


• Efavirenz


• Etravirine


• Fosamprenavir


• Fosaprepitant


• Fosphenytoin


• Ginseng


• Griseofulvin


• Lamotrigine


• Licorice


• Minocycline


• Modafinil


• Mycophenolate Mofetil


• Mycophenolic Acid


• Nelfinavir


• Nevirapine


• Oxcarbazepine


• Oxytetracycline


• Phenobarbital


• Phenytoin


• Pioglitazone


• Prednisolone


• Primidone


• Rifabutin


• Rifampin


• Rifapentine


• Ritonavir


• Roflumilast


• Rosuvastatin


• Rufinamide


• Selegiline


• St John's Wort


• Telaprevir


• Tetracycline


• Tipranavir


• Topiramate


• Troglitazone


• Troleandomycin


• Valdecoxib


• Voriconazole


• Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Caffeine


• Grapefruit Juice

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Abnormal or unusual vaginal bleeding or


• Adrenal disease or


• Blood clots, or history of or


• Breast cancer, active or history of or


• Diabetes with kidney, eye, nerve, or blood vessel damage or


• Heart attack, history of or


• Heart or blood vessel disease or


• Heart rhythm problems or


• Hypertension (high blood pressure), uncontrolled or


• Kidney disease or


• Liver disease, including tumors or cancer or


• Migraine headache, new or worse or a new kind of headache or


• Problems with circulation or blood clots, now or in the past or


• Problems with heart valves or


• Stroke, history of—Should not be used in patients with these conditions.

• Angioedema (swelling of the face, tongue, or throat), inherited or


• Chloasma gravidarum (skin disorder during pregnancy), history of or


• Cholestasis (bile problem) during pregnancy, history of or


• Depression, history of or


• Diabetes or


• Dyslipidemia (high cholesterol or fats in the blood), uncontrolled or


• Gallbladder disease or


• Hyperkalemia (high potassium in the blood) or


• Hypertension (high blood pressure), controlled—Use with caution. May make these conditions worse.

Proper Use of drospirenone, ethinyl estradiol, and levomefolate

This section provides information on the proper use of a number of products that contain drospirenone, ethinyl estradiol, and levomefolate. It may not be specific to Beyaz. Please read with care.

To make using hormonal contraceptives as safe and reliable as possible, you should understand how and when to use them and what effects may be expected.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

This medicine is available in blister packs. Each blister pack contains 28 tablets with different colors that need to be taken in the same order as directed on the blister pack.

When you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented. Use a second form of contraception, such as a condom, spermicide, or diaphragm, for the first 7 days of your first cycle of pills.

Take this medicine at the same time each day, after the evening meal or at bedtime. You may take this medicine with or without food.

Do not skip or delay taking your pill by more than 24 hours. If you miss a dose, you could get pregnant. Ask your doctor for ways to help you remember to take your pills or about using another method of birth control.

You may have light bleeding or spotting when you first take the pill.

You may feel sick or nauseous, especially during the first few months that you take this medicine. If your nausea is continuous and does not go away, call your doctor.

If you vomit or have diarrhea within 3 to 4 hours of taking this medicine, follow the instructions in the patient leaflet or call your doctor.

If you are switching from a combination hormonal method (e.g., another pill, patch, vaginal ring) to using Beyaz® or Safyral™, take this medicine on the first day of your period. If you do not start your period, see your doctor for a pregnancy test. If you have used a vaginal ring or patch, take the pill on the day the ring or patch is removed. You must also use a second method of birth control (e.g., condom, diaphragm, spermicide) for the first 7 days you take this medicine.

If you are switching from a progestin-only method (e.g., progestin-only pill, implant, injection, intrauterine system) to using Beyaz® or Safyral™, take the medicine on the day you would have taken your next progestin-only pill, or on the day your implant or IUD is removed, or on the day you would have your next injection. You must also use a second method of birth control (e.g., condom, diaphragm, spermicide) for the first 7 days you take this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Your doctor may ask you to begin your dose on the first day of your menstrual period (called Day 1 Start) or on the first Sunday after your menstrual period starts (called Sunday Start). When you begin on a certain day it is important that you follow that schedule, even if you miss a dose. Do not change your schedule on your own. If the schedule that you use is not convenient, check with your doctor about changing it. For a Sunday start, you need to use another form of birth control (e.g., condom, diaphragm, spermicide) for the first 7 days.

• For oral dosage form (tablets):
  
  • For contraception (to prevent pregnancy), PMDD, or acne:
    
    • Adults and teenagers—One tablet taken at the same time each day for 28 days.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Beyaz

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and does not cause unwanted effects. These visits will usually be every 6 to 12 months, but some doctors require them more often.

Although you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.

Vaginal bleeding of various amounts may occur between your regular menstrual periods during the first 3 months of use. This is sometimes called spotting when slight, or breakthrough bleeding when heavier.

• If this should occur, continue with your regular dosing schedule.


• The bleeding usually stops within 1 week. Check with your doctor if the bleeding continues for more than 1 week.


• If bleeding continues after you have been taking hormonal contraceptives on schedule and for more than 3 months, check with your doctor.

Check with your doctor right away if you miss a menstrual period. Missed periods may occur if you skip one or more pink tablets and have not taken your pills exactly as directed. If you miss two periods in a row, talk to your doctor. You might need a pregnancy test.

If you suspect that you may be pregnant, stop using this medicine immediately and check with your doctor. You should continue to take folate supplements.

Do not use this medicine if you smoke cigarettes or if you are over 35 years old. If you smoke while using birth control pills, you increase your risk of having a heart attack, stroke, or blood clot. Your risk is even higher if you are over age 35, if you have diabetes, high blood pressure, high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. Keep your diabetes under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.

Stop using this medicine and check with your doctor right away if you have pain in the chest, groin, or legs, especially the calves; difficulty with breathing; a sudden, severe headache; slurred speech; a sudden, unexplained shortness of breath; a sudden loss of coordination; or vision changes while using this medicine.

Check with your doctor immediately if you have problems wearing contact lenses or if blurred vision, difficulty with reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Stop using this medicine and check with your doctor right away if you have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.

Check with your doctor before refilling an old prescription, especially after a pregnancy. You will need another physical examination and your doctor may change your prescription.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or certain medical tests.

This medicine may cause skin discoloration. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (e.g., St. John's wort) or vitamin supplements.

Beyaz Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Breast pain or tenderness


• headache, severe and throbbing


• heavy nonmenstrual vaginal bleeding


• irregular menstrual periods


• nausea


• normal menstrual bleeding occurring earlier, possibly lasting longer than expected

Less common

• Longer or heavier menstrual periods


• unusual tiredness or weakness


• vomiting

Incidence not known

• Abdominal or stomach pain


• chills


• clay-colored stools


• dark urine


• difficulty with breathing


• dizziness


• fever


• headache


• itching


• loss of appetite


• pain in the chest, groin, or legs, especially the calves


• rash


• slurred speech


• sudden loss of coordination


• sudden, severe weakness or numbness in the arm or leg


• sudden, unexplained shortness of breath


• unpleasant breath odor


• unusual tiredness or weakness


• vision changes


• vomiting of blood


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Crying


• decreased interest in sexual intercourse


• delusions of persecution, mistrust, suspiciousness, and/or combativeness


• false or unusual sense of well-being


• inability to have or keep an erection


• irritability


• loss in sexual ability, desire, drive, or performance


• mental depression


• quick to react or overreact emotionally


• rapidly changing moods


• weight gain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Beyaz side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Beyaz resources

• Beyaz Side Effects (in more detail)
• Beyaz Use in Pregnancy & Breastfeeding
• Beyaz Drug Interactions
• Beyaz Support Group
• 58 Reviews for Beyaz - Add your own review/rating

• Beyaz Prescribing Information (FDA)


• Beyaz Consumer Overview


• Beyaz MedFacts Consumer Leaflet (Wolters Kluwer)


• Safyral Prescribing Information (FDA)


• Safyral Consumer Overview


• Safyral MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Beyaz with other medications

• Acne
• Birth Control
• Premenstrual Dysphoric Disorder

Betoptic-S Drops

Pronunciation: be-TAX-oh-lol
Generic Name: Betaxolol
Brand Name: Betoptic-S

Betoptic-S Drops are used for:

Treating increased pressure in the eye (ocular hypertension) and open-angle glaucoma. It may be used alone or with other medicines. It may also be used for other conditions as determined by your doctor.

Betoptic-S Drops are a beta-blocker for use in the eye. It works by decreasing fluid production and pressure inside the eye.

Do NOT use Betoptic-S Drops if:

• you are allergic to any ingredient in Betoptic-S Drops


• you have greater than first-degree heart block, shock caused by severe heart problems, uncontrolled heart failure, or a very slow heartbeat

Contact your doctor or health care provider right away if any of these apply to you.

Before using Betoptic-S Drops:

Some medical conditions may interact with Betoptic-S Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have bronchitis, narrow-angle glaucoma (angle-closure glaucoma), double vision, a drooping eyelid, an eye infection or injury, certain muscle problems (eg, myasthenia gravis, muscle weakness), or an overactive thyroid


• if you have a history of lung or breathing problems (eg, asthma, chronic obstructive pulmonary disease [COPD]), heart problems (eg, heart failure, irregular heartbeat), diabetes, low blood sugar levels (hypoglycemia), or blood vessel problems (eg, in the brain, in the hands and feet)


• if you have had or will be having eye surgery


• if you are taking an oral beta-blocker (eg, metoprolol)

Some MEDICINES MAY INTERACT with Betoptic-S Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Diltiazem, flecainide, or verapamil because they may increase the risk of Betoptic-S Drops's side effects


• Alfuzosin or prazosin because if low blood pressure occurs after their first dose, Betoptic-S Drops may cause it to be more severe or to last longer


• Clonidine because high blood pressure may occur in some cases, especially if you suddenly stop taking clonidine while taking Betoptic-S Drops


• Insulin or oral diabetes medicines (eg, glyburide) because the risk of low blood sugar levels may be increased


• Reserpine because the risk of its side effects may be increased by Betoptic-S Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Betoptic-S Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Betoptic-S Drops:

Use Betoptic-S Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• If you use other medicines in the eye, use them at least 10 minutes before using Betoptic-S Drops.


• Shake well before each use.


• To use Betoptic-S Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Instill Betoptic-S Drops into your eye as directed. Gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid (unless you recently had eye surgery) for 1 to 2 minutes. Do not blink.


• Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.


• Ask your doctor how to use your contact lenses while using Betoptic-S Drops.


• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.


• Using Betoptic-S Drops at the same time each day will help you remember to use it.


• Continue to use Betoptic-S Drops even if you feel well. Do not miss any doses.


• If you miss a dose of Betoptic-S Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Betoptic-S Drops.

Important safety information:

• Betoptic-S Drops may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Betoptic-S Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Tell your doctor or dentist that you take Betoptic-S Drops before you receive any medical or dental care, emergency care, or surgery.


• If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using Betoptic-S Drops.


• Diabetes patients - Betoptic-S Drops may hide signs of low blood sugar, such as a rapid heartbeat. Be sure to watch for other signs of low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Betoptic-S Drops may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.


• Lab tests, including eye pressure checks, may be performed while you use Betoptic-S Drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Betoptic-S Drops while you are pregnant. It is not known if Betoptic-S Drops are found in breast milk. If you are or will be breast-feeding while you use Betoptic-S Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Betoptic-S Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; crusty lashes; dry eyes; mild burning, stinging, itching, or tearing; mild eye discomfort, pain, redness, or discharge; sensation of something in the eye.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); drooping eyelid; red, swollen, blistered, or peeling skin; sensitivity to light; severe or persistent dizziness; shortness of breath; slow or irregular heartbeat; sudden, unexplained weight gain; swelling of the hands, ankles, legs, or feet; unusual weakness; vision changes (eg, decreased vision clearness, double vision); wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Betoptic-S side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness; fainting; shortness of breath; slow heartbeat; sudden, unexplained weight gain; swelling of the hands, ankles, legs, or feet. Betoptic-S Drops may be harmful if swallowed.

Proper storage of Betoptic-S Drops:

Store Betoptic-S Drops upright between 36 and 77 degrees F (2 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Betoptic-S Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Betoptic-S Drops, please talk with your doctor, pharmacist, or other health care provider.


• Betoptic-S Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Betoptic-S Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Betoptic-S resources

• Betoptic-S Side Effects (in more detail)
• Betoptic-S Use in Pregnancy & Breastfeeding
• Betoptic-S Drug Interactions
• 0 Reviews for Betoptic-S - Add your own review/rating

Compare Betoptic-S with other medications

• Glaucoma, Open Angle
• Intraocular Hypertension

Bexxar 131 Iodine

Pronunciation: EYE-oh-dine/tos-IT-too-moe-mab
Generic Name: Iodine I 131/Tositumomab
Brand Name: Bexxar 131 Iodine

Bexxar 131 Iodine may cause serious allergic reactions, especially in patients who have received murine proteins previously. Seek immediate medical attention if you experience rash, itching, swelling, severe dizziness, or trouble breathing. Bexxar 131 Iodine may cause serious (possibly life-threatening) decreases in the number of white blood cells and platelets your body produces. This effect may last for a long period of time. Additional treatment may be needed to manage this effect. Serious infections or bleeding could occur as a result of low blood cell levels. Contact your doctor immediately if you experience fever, persistent sore throat, any other sign of infection, or unusual bruising or bleeding. Bexxar 131 Iodine must not be used during pregnancy because fetal harm can result. Contact your doctor immediately if you suspect that you could be pregnant.

Bexxar 131 Iodine is used for:

Treating certain forms of non-Hodgkin lymphoma in patients who have not responded to other therapy.

Bexxar 131 Iodine is a radioactive monoclonal antibody protein. It works by recognizing a protein receptor on cancer cells and then delivering radiation that increases the killing effect of the antibody.

Do NOT use Bexxar 131 Iodine if:

• you are allergic to any ingredient in Bexxar 131 Iodine or to mouse proteins


• you have bone marrow depression or a serious blood disorder such as low hemoglobin, white blood cells, or platelets


• you are pregnant


• you are unable to take a thyroid blocker (eg, methimazole)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Bexxar 131 Iodine:

Some medical conditions may interact with Bexxar 131 Iodine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are planning to become pregnant or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have an infection, thyroid problems, or kidney problems


• if you are scheduled to receive a vaccine

Some MEDICINES MAY INTERACT with Bexxar 131 Iodine. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Medicines that decrease blood clotting (eg, aspirin, clopidogrel, ibuprofen, warfarin) and medicines that affect the immune system (eg, azathioprine, corticosteroids, cyclosporine) because serious side effects, such as risk of bleeding or infections, may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Bexxar 131 Iodine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bexxar 131 Iodine:

Use Bexxar 131 Iodine as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Bexxar 131 Iodine is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor any question that you may have about Bexxar 131 Iodine.


• If you miss a dose of Bexxar 131 Iodine, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Bexxar 131 Iodine.

Important safety information:

• Bexxar 131 Iodine may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Bexxar 131 Iodine. Using Bexxar 131 Iodine alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.


• Bexxar 131 Iodine may reduce the number of certain blood cells, including red blood cells, white blood cells, and platelets. This may increase your risk of infection and bleeding. Prevent infection by avoiding contact with people with colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first. Notify your doctor of any signs of infection, including fever, sore throat, rashes, or chills. To prevent bleeding, avoid situations in which bruising or injury may occur. Report any unusual bleeding or bruising; blood in stools; or black, tarry stools to your doctor.


• Avoid vaccinations with live virus vaccines (eg, measles, mumps, oral polio) while you are taking Bexxar 131 Iodine.


• As with other cancer medicines, Bexxar 131 Iodine can cause a secondary cancer. Discuss the benefits and risks of using Bexxar 131 Iodine with your doctor.


• After receiving Bexxar 131 Iodine, the radioactive part of the dose will be in your body for several days. Follow all instructions you are given to minimize the exposure of others around you to this radioactivity.


• Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Bexxar 131 Iodine.


• Bexxar 131 Iodine may reduce the levels of thyroid hormone your thyroid produces. Thyroid tests will be done before your doses and every year thereafter to monitor for any change in function of the thyroid gland.


• Some patients may develop an immune response called HAMA (human anti-murine antibody) after using Bexxar 131 Iodine. This antibody may interfere with certain lab test results. Be sure all of your doctors and laboratory personnel know that you are being treated, or have been treated, with Bexxar 131 Iodine.


• Both men and women capable of having children who receive Bexxar 131 Iodine should use reliable methods of birth control (eg, condoms) during and for at least 1 year after receiving Bexxar 131 Iodine.


• LAB TESTS, including complete blood cell counts, platelet counts, thyroid function tests, and kidney function tests, will be required to monitor your progress and check for side effects. Frequent monitoring will be done for up to 12 weeks after treatment. Be sure to keep all doctor and lab appointments.


• Caution is advised when using Bexxar 131 Iodine in the ELDERLY because they may be more sensitive to the effect Bexxar 131 Iodine has on blood cells.


• PREGNANCY and BREAST-FEEDING: Do not use Bexxar 131 Iodine if you are pregnant. If you think that you may be pregnant, contact your doctor immediately. Bexxar 131 Iodine is excreted in breast milk. Do not breast-feed while receiving Bexxar 131 Iodine.

Possible side effects of Bexxar 131 Iodine:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; headache; muscle aches; nausea; pain, swelling, or redness at the injection site; stomach upset; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black stools; easy bruising or bleeding; fast heartbeat; flu-like symptoms such as chills, cough, or sweating; infection; itching; lightheadedness; loss of appetite; lung infection; new growths or lumps; pain, including chest, stomach, muscle, neck, back, or joint pain; pale skin; persistent sore throat or fever; shortness of breath; sudden weight loss; swelling of the hands or feet; unusual tiredness or weakness; vomit that looks like coffee grounds.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Bexxar31 Iodine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Bexxar 131 Iodine:

Bexxar 131 Iodine is radioactive and must be stored in the lead pot provided. It is usually handled and stored by a health care professional. Keep Bexxar 131 Iodine out of reach of children and away from pets.

General information:

• If you have any questions about Bexxar 131 Iodine, please talk with your doctor, pharmacist, or other health care provider.


• Bexxar 131 Iodine is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Bexxar 131 Iodine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Bexxar 131 Iodine resources

• Bexxar 131 Iodine Side Effects (in more detail)
• Bexxar 131 Iodine Use in Pregnancy & Breastfeeding
• Bexxar 131 Iodine Drug Interactions
• Bexxar 131 Iodine Support Group
• 0 Reviews for Bexxar31 Iodine - Add your own review/rating

Compare Bexxar 131 Iodine with other medications

• Non-Hodgkin's Lymphoma

betaxolol ophthalmic

Generic Name: betaxolol ophthalmic (bay TAX oh lol off THAL mik)

Brand names: Betoptic S, Betoptic

What is betaxolol ophthalmic?

Betaxolol is a beta-blocker that reduces pressure inside the eye.

Betaxolol ophthalmic (for the eyes) is used to treat open-angle glaucoma and other causes of high pressure inside the eye.

Betaxolol ophthalmic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about betaxolol ophthalmic?

Do not use this medication if you are allergic to betaxolol, or if you have asthma, or severe chronic obstructive pulmonary disease (COPD), slow heartbeats, or a heart condition called "AV block."

Before using this medication, tell your doctor if you have breathing problems such as bronchitis or emphysema, a history of heart disease or congestive heart failure, diabetes, history of stroke, blood clot, or circulation problems, a thyroid disorder, or a muscle disorder such as myasthenia gravis.

Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Betaxolol ophthalmic is sometimes given together with other eye medications. Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using betaxolol ophthalmic. Do not use the medications at the same time.

Betaxolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly. Do not use this medication while you are wearing contact lenses. Betaxolol ophthalmic may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using betaxolol before putting your contact lenses in.

What should I discuss with my healthcare provider before using betaxolol ophthalmic?

Do not use this medication if you are allergic to betaxolol, or if you have:

• 
  

  asthma, or severe chronic obstructive pulmonary disease (COPD);

  
  


• 
  

  slow heartbeats; or

  
  


• 
  

  a heart condition called "AV block."

  
  

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• 
  

  breathing problems such as bronchitis or emphysema;

  
  


• 
  

  a history of heart disease or congestive heart failure;

  
  


• 
  

  diabetes;

  
  


• 
  

  history of stroke, blood clot, or circulation problems;

  
  


• 
  

  a thyroid disorder; or

  
  


• 
  

  a muscle disorder such as myasthenia gravis.

  
  

FDA pregnancy category C. It is not known whether betaxolol ophthalmic is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether betaxolol passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use betaxolol ophthalmic?

Use betaxolol ophthalmic exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Wash your hands before using the eye drops. Do not use this medication while you are wearing contact lenses. Betaxolol ophthalmic may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using betaxolol before putting your contact lenses in.

To apply the eye drops:

• 
  

  Tilt your head back slightly and pull down your lower eyelid. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

  
  


• 
  

  Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

  
  


• 
  

  Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

  
  

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Tell your doctor right away if you have any eye injury or infection. If you have any type of surgery, including eye surgery, tell the surgeon ahead of time that you are using betaxolol ophthalmic. You may need to stop using the medicine for a short time. Store this medication at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include slow heart rate, feeling short of breath, swelling, rapid weight gain, or fainting.

What should I avoid while using betaxolol ophthalmic?

Betaxolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Betaxolol ophthalmic is sometimes given together with other eye medications. Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using betaxolol ophthalmic. Do not use the medications at the same time.

Betaxolol ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  severe swelling, itching, burning, redness, pain, or discomfort in or around your eye;

  
  


• 
  

  drainage, crusting, or oozing of your eyes or eyelids;

  
  


• 
  

  bronchospasm (wheezing, chest tightness, trouble breathing);

  
  


• 
  

  slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);

  
  


• 
  

  feeling short of breath, even with mild exertion; or

  
  


• 
  

  swelling, rapid weight gain.

  
  

Less serious side effects may include:

• 
  

  mild burning, stinging, itching, or discomfort of your eyes;

  
  


• 
  

  dry eyes, blurred vision;

  
  


• 
  

  mildly swollen or puffy eyes;

  
  


• 
  

  feeling like something is in your eye;

  
  


• 
  

  headache, dizziness, spinning sensation;

  
  


• 
  

  depression;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  muscle weakness; or

  
  


• 
  

  altered sense of taste or smell.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Betaxolol ophthalmic Dosing Information

Usual Adult Dose for Intraocular Hypertension:

Instill 1 to 2 drops in the affected eye(s) twice daily.

Usual Adult Dose for Glaucoma (Open Angle):

Instill 1 to 2 drops in the affected eye(s) twice daily.

What other drugs will affect betaxolol ophthalmic?

Before using betaxolol ophthalmic, tell your doctor if you are using any of the following drugs:

• 
  

  oral betaxolol (Blocadren);

  
  


• 
  

  digoxin (digitalis, Lanoxin);

  
  


• 
  

  reserpine;

  
  


• 
  

  insulin or diabetes medications you take by mouth;

  
  


• 
  

  any other beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), timolol (Blocadren), and others;

  
  


• 
  

  a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan); or

  
  


• 
  

  medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), or thioridazine (Mellaril).

  
  

This list is not complete and there may be other drugs that can interact with betaxolol ophthalmic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More betaxolol ophthalmic resources

• Betaxolol ophthalmic Dosage
• Betaxolol ophthalmic Use in Pregnancy & Breastfeeding
• Betaxolol ophthalmic Drug Interactions
• Betaxolol ophthalmic Support Group
• 0 Reviews for Betaxolol - Add your own review/rating

• Betoptic Prescribing Information (FDA)


• Betoptic S Prescribing Information (FDA)


• Betoptic S eent Monograph (AHFS DI)


• Betoptic S Advanced Consumer (Micromedex) - Includes Dosage Information

Compare betaxolol ophthalmic with other medications

• Glaucoma, Open Angle
• Intraocular Hypertension

Where can I get more information?

• Your pharmacist can provide more information about betaxolol ophthalmic.

bexarotene topical

Generic Name: bexarotene topical (beks AIR oh teen)

Brand Names: Targretin Topical

What is bexarotene topical?

The exact way bexarotene works is unknown, but it is believed to inhibit the growth of tumor cells.

Bexarotene topical is used to treat skin lesions of cutaneous T-cell lymphoma (CTCL) (Stage 1A and 1B) in patients who have not responded to or not tolerated other therapies.

Bexarotene topical may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about bexarotene topical?

Avoid prolonged exposure to sunlight or artificial ultraviolet light (e.g. sunlamps). Bexarotene topical may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Do not use bexarotene topical if you are pregnant or if you could become pregnant. Bexarotene topical is in the FDA pregnancy category X. This means that bexarotene topical will cause birth defects in an unborn baby. You must take a pregnancy test and have negative results within one week before starting treatment with bexarotene topical, and a pregnancy test should be repeated monthly during treatment. Bexarotene topical should be started on the second or third day of a normal menstrual period. Also, you will need to use two reliable forms of birth control at the same time for one month before starting treatment with bexarotene topical, during treatment with bexarotene topical, and for at least 1 month following the end of your treatment. If you become pregnant, stop using birth control, or miss your menstrual period, immediately stop using bexarotene topical and notify your doctor. Men using bexarotene topical with sexual partners who are pregnant, possibly pregnant, or who could become pregnant, must use condoms during sexual intercourse while using bexarotene topical and for at least one month after the last dose of bexarotene topical.

Who should not use bexarotene topical?

Do not use bexarotene topical without first talking to your doctor if you are allergic to other retinoids such as isotretinoin (Accutane), acitretin (Soriatane), etretinate (Tegison), or tretinoin (Vesinoid). Before using bexarotene topical, tell your doctor if you have kidney or liver disease. You may not be able to use bexarotene topical, or you may require a dosage adjustment or special monitoring during treatment. Do not use bexarotene topical if you are pregnant or if you could become pregnant. Bexarotene topical is in the FDA pregnancy category X. This means that bexarotene topical will cause birth defects in an unborn baby. You must take a pregnancy test and have negative results within one week before starting treatment with bexarotene topical, and a pregnancy test should be repeated monthly during treatment. Bexarotene topical should be started on the second or third day of a normal menstrual period. Also, you will need to use two reliable forms of birth control at the same time for one month before starting treatment with bexarotene topical, during treatment with bexarotene topical, and for at least 1 month following the end of your treatment. If you become pregnant, stop using birth control, or miss your menstrual period, immediately stop using bexarotene topical and notify your doctor. Men using bexarotene topical with sexual partners who are pregnant, possibly pregnant, or who could become pregnant, must use condoms during sexual intercourse while using bexarotene topical and for at least one month after the last dose of bexarotene topical. It is not known whether bexarotene topical passes into breast milk. Do not take bexarotene topical without first talking to your doctor if you are breast-feeding a baby.

How should I use bexarotene topical?

Use bexarotene topical exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Wash your hands with soap and water before and after applying this medication.

Apply enough gel to cover the affected area with a generous coating. Proper application should leave some gel visible on the surface of the lesion. Allow the gel to dry for 5 to 10 minutes before covering with clothing.

Do not use bandages, dressings, or other coverings, other than loose clothing, that block the flow of air to the treated area. Do not apply bexarotene topical to unaffected skin. In addition, do not apply the gel near the eyes, mouth, nostrils, lips, vagina, tip of the penis, rectum, or anus. If you get medication on any of these areas, rinse it off with water.

Mild, non-deodorant soap is recommended for bathing or showering. Wait for 20 minutes after bathing or showering before applying bexarotene topical. Wait for at least 3 hours after applying bexarotene topical before bathing, showering, or swimming.

Bexarotene topical is initially applied once every other day for the first week. The application frequency is then usually increased at weekly intervals to once daily, then three times daily, and finally four times daily according to how well treatment is tolerated. If the affected area becomes irritated, the frequency of application can be reduced. If severe irritation occurs, application can be temporarily stopped for a few days until the irritation is reduced. Follow your doctor's instructions.

Avoid scratching the treated areas.

It may take many weeks of treatment to see the effects of this drug. Do not stop using bexarotene topical if you do not see results immediately. Treatment with bexarotene topical should continue for as long as beneficial effects are being obtained.

Store bexarotene topical at room temperature away from moisture and heat.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for your next application, skip the missed application and apply only the next regularly scheduled dose.Do Notapply a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

An overdose of this medication is unlikely to occur. If you do suspect an overdose, or if bexarotene topical has been ingested, call an emergency room or poison control center near you.

What should I avoid while using bexarotene topical?

Avoid prolonged exposure to sunlight or artificial ultraviolet light (e.g. sunlamps). Bexarotene topical may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Do not use bandages, dressings, or other coverings, other than loose clothing, that block the flow of air to the treated area.

Wait for at least 3 hours after applying bexarotene topical before bathing, showering, or swimming.

Avoid scratching the treated areas.

Vitamin A may increase side effects when using bexarotene topical. Limit your use of vitamin A supplements to not more than the recommended daily allowance (RDA) of 4000 to 5000 International Units (IU) a day.

Do not use insect repellents or other products that contain DEET (N,N-diethyl-m-toluamide) while using bexarotene topical. Bexarotene topical may increase DEET toxicity, which could be dangerous.

Avoid using other topical products on the affected area at the same time as bexarotene topical unless otherwise directed by your doctor. These products may interfere with the effects or absorption of bexarotene topical.

The Targretin Topical gel brand of bexarotene topical contains alcohol and should be kept away from open flames.

Bexarotene topical side effects

Serious side effects are not likely to occur. Stop using bexarotene topical and seek emergency medical attention if you experience an allergic reaction (shortness of breath; closing of your throat; swelling of your lips, face, or tongue; or hives).

You may experience some redness, itching, warmth, swelling, burning, scaling, or other irritation while you are using bexarotene topical. If these side effects are excessive, talk to your doctor. Your doctor may prescribe less frequent applications of bexarotene topical.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Bexarotene topical Dosing Information

Usual Adult Dose for Cutaneous T-cell Lymphoma:

A sufficient quantity of gel to cover the lesion(s) with a generous coating should be applied topically initially once every other day for the first week. Thereafter, the frequency of application should be increased at weekly intervals to once a day, then twice a day, then three times a day, and finally to four times a day according to individual lesion tolerance. Generally, most patients are able to tolerate twice a day to four times a day applications.

What other drugs will affect bexarotene topical?

Vitamin A my increase side effects when using bexarotene topical. Limit your use of vitamin A supplements to not more than 15, 000 units (IU) a day.

Do not use insect repellents or other products that contain DEET (N,N-diethyl-m-toluamide) while using bexarotene topical. Bexarotene topical may increase DEET toxicity, which could be dangerous.

Avoid using other topical products on the affected area at the same time as bexarotene topical unless otherwise directed by your doctor. These products may interfere with the effects or

Drugs other than those listed here may also interact with bexarotene topical. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More bexarotene topical resources

• Bexarotene topical Dosage
• Bexarotene topical Use in Pregnancy & Breastfeeding
• Bexarotene topical Drug Interactions
• Bexarotene topical Support Group
• 0 Reviews for Bexarotene - Add your own review/rating

Compare bexarotene topical with other medications

• Cutaneous T-cell Lymphoma

Where can I get more information?

• Your pharmacist has additional information about bexarotene topical written for health professionals that you may read.

Betatar Gel

Generic Name: coal tar topical (KOL TAR TOP ik al)

Brand Names: Balnetar, Betatar Gel, Coal Tar, Cutar, Denorex, Denorex Dry Scalp, Denorex Extra Strength, Denorex Medicated Shampoo and Conditioner, DHS Tar Shampoo, Doak Tar, Doak Tar Oil, Elta Tar, Fototar, G-TAR, Ionil T, Ionil T Plus, MG 217 Psoriasis, MG217 Medicated Tar, Neutrogena T/Derm, Neutrogena T/Gel, Neutrogena T/Gel Extra Strength, Oxipor VHC, PC Tar, Pentrax, Pentrax Gold, Polytar, Psoriasin, Psorigel, T/Gel Conditioner, Tegrin Medicated, Tegrin Medicated Soap, Therapeutic, Theraplex T, Zetar

What is coal tar?

Coal tar is a by-product of coal processing.

Coal tar topical (for the skin) is used to treat the skin symptoms of psoriasis, including dryness, redness, flaking, scaling, and itching. Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.

Coal tar may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about coal tar?

You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.

Do not use coal tar to treat the skin of your groin or rectal area.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.

Coal tar is not a cure for psoriasis, and it will provide only temporary relief of skin symptoms.

What should I discuss with my health care provider before using coal tar?

You should not use this medication if you are allergic to coal tar.

Before using coal tar, tell your doctor if you are allergic to any drugs, or if you are receiving ultraviolet radiation treatment for your psoriasis.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether coal tar passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Coal tar products may contain lanolin, mineral oil, or other emulsifiers. Check the label of any coal tar product you are using. Talk with your doctor before using coal tar if you are allergic to any of the ingredients.

How should I use coal tar?

Use this medication as directed on the label, or as your doctor has prescribed. Do not use the medication in larger amounts or for longer than recommended.

Apply coal tar cream, lotion, ointment, or solution according the directions on the medication label. Some forms of coal tar may be applied 1 to 4 times per day.

To use coal tar bath oil, pour 1 to 3 capfuls into a warm bath before bathing. The oil can make the bathtub slippery. Take care to avoid a fall.

Shake the coal tar shampoo well just before each use. Use enough shampoo to create a rich lather. Massage the shampoo into your scalp and rinse thoroughly. Apply the shampoo a second time and leave it on your scalp for 5 minutes. Rinse thoroughly. Do not use coal tar to treat large skin areas. Do not use coal tar over long periods of time without your doctor's advice.

Call your doctor if your symptoms do not improve, or if they get worse after using coal tar.

Coal tar shampoo may discolor blond or colored hair. This effect is usually temporarily.

Some forms of coal tar can stain fabric or other surfaces.

Store coal tar at room temperature away from moisture and heat. Keep the medicine tightly closed with not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a coal tar overdose are not known.

What should I avoid while using coal tar?

Avoid getting this medication in your eyes. If this does occur, rinse with water.

Do not use coal tar to treat the skin of your groin or rectal area.

Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Coal tar can make your skin more sensitive to sunlight and sunburn may result.

Coal tar side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using coal tar and call your doctor at once if you have severe stinging, burning, swelling, or other irritation of the treated skin.

Less serious side effects may include mild skin irritation or skin rash.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect coal tar?

Do not use coal tar together with other psoriasis medications unless your doctor tells you to.

There may be other drugs that can interact with coal tar. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Betatar Gel resources

• Betatar Gel Use in Pregnancy & Breastfeeding
• Betatar Gel Support Group
• 0 Reviews for Betatar - Add your own review/rating

• Betatar Gel Topical Advanced Consumer (Micromedex) - Includes Dosage Information


• Coal Tar Foam MedFacts Consumer Leaflet (Wolters Kluwer)


• Denorex Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)


• Doak Tar Shampoo MedFacts Consumer Leaflet (Wolters Kluwer)


• Fototar Ointment MedFacts Consumer Leaflet (Wolters Kluwer)


• MG217 Medicated Tar Lotion MedFacts Consumer Leaflet (Wolters Kluwer)


• Psoriasin Prescribing Information (FDA)

Compare Betatar Gel with other medications

• Dermatitis
• Psoriasis
• Seborrheic Dermatitis

Where can I get more information?

• Your pharmacist can provide more information about coal tar.

Betimol

Generic Name: timolol ophthalmic (TIM oh lol off THAL mik)

Brand Names: Betimol, Istalol, Timoptic Ocudose, Timoptic Ocumeter, Timoptic Ocumeter Plus, Timoptic-XE

What is Betimol (timolol ophthalmic)?

Timolol is a beta-blocker that also reduces pressure inside the eye.

Timolol ophthalmic (for the eyes) is used to treat open-angle glaucoma and other causes of high pressure inside the eye.

Timolol ophthalmic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Betimol (timolol ophthalmic)?

Do not allow the dropper to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using timolol ophthalmic. Do not use the medications at the same time.

Timolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

What should I discuss with my healthcare provider before using Betimol (timolol ophthalmic)?

Do not use this medication if you are allergic to timolol, or if you have:

• 
  

  asthma or severe chronic obstructive pulmonary disease (COPD);

  
  


• 
  

  certain serious heart conditions, especially "AV block"; or

  
  


• 
  

  severe or uncontrolled congestive heart failure.

  
  

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• 
  

  breathing problems such as bronchitis or emphysema;

  
  


• 
  

  a history of heart disease or congestive heart failure;

  
  


• 
  

  diabetes;

  
  


• 
  

  history of stroke, blood clot, or circulation problems;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  a muscle disorder such as myasthenia gravis;

  
  


• 
  

  kidney disease; or

  
  


• 
  

  liver disease.

  
  

FDA pregnancy category C. It is not known whether timolol ophthalmic is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Timolol ophthalmic passes into breast milk and could cause harm to a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medicine for a child younger than 2 years old.

How should I use Betimol (timolol ophthalmic)?

Use timolol ophthalmic exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

Wash your hands before using the eye drops. Do not use this medication while you are wearing contact lenses. Timolol ophthalmic may contain a preservative that can be absorbed by soft contact lenses. Wait at least 15 minutes after using timolol before putting your contact lenses in.

To apply the eye drops:

• 
  

  Tilt your head back slightly and pull down your lower eyelid. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

  
  


• 
  

  Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

  
  


• 
  

  Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

  
  

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

If you need to have any type of surgery, especially eye surgery, tell the surgeon ahead of time that you are using timolol ophthalmic. You may need to stop using the medicine for a short time.

Store this medication at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling dizzy or short of breath, headache, slow heart beat, chest pain, or fainting.

What should I avoid while using Betimol (timolol ophthalmic)?

Timolol ophthalmic can cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using timolol ophthalmic. Do not use the medications at the same time.

Betimol (timolol ophthalmic) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  swelling or redness of your eyelids;

  
  


• 
  

  eye redness, discomfort, or sensitivity to light;

  
  


• 
  

  drainage, crusting, or oozing of your eyes or eyelids;

  
  


• 
  

  depressed mood, confusion, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  wheezing, gasping, or other breathing problems;

  
  


• 
  

  swelling, rapid weight gain;

  
  


• 
  

  chest pain, slow or uneven heart rate; or

  
  


• 
  

  feeling short of breath, even with mild exertion.

  
  

Less serious side effects may include:

• 
  

  blurred vision, double vision, drooping eyelid;

  
  


• 
  

  burning or stinging in your eye;

  
  


• 
  

  headache, weakness, drowsiness;

  
  


• 
  

  numbness, tingling, or cold feeling in your hands or feet;

  
  


• 
  

  ringing in your ears;

  
  


• 
  

  dry mouth;

  
  


• 
  

  nausea, diarrhea, loss of appetite, upset stomach;

  
  


• 
  

  skin rash or worsening psoriasis;

  
  


• 
  

  sleep problems (insomnia); or

  
  


• 
  

  cough, stuffy nose.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Betimol (timolol ophthalmic)?

Before using timolol ophthalmic, tell your doctor if you are using any of the following drugs:

• 
  

  clonidine (Catapres);

  
  


• 
  

  quinidine (Cardioquin, Quinadex, Quinaglute);

  
  


• 
  

  reserpine;

  
  


• 
  

  digitalis (digoxin, Lanoxin, Lanoxicaps);

  
  


• 
  

  acetazolamide (Diamox), dichlorphenamide (Daranide), or methazolamide (Neptazane);

  
  


• 
  

  oral timolol (Blocadren);

  
  


• 
  

  any other beta-blocker such as atenolol (Tenormin), bisoprolol (Zebeta), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), penbutolol (Levatol), pindolol (Visken), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;

  
  


• 
  

  a calcium channel blocker such as diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nifedipine (Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan), and others; or

  
  


• 
  

  antidepressants such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).

  
  

This list is not complete and there may be other drugs that can interact with timolol ophthalmic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Betimol resources

• Betimol Side Effects (in more detail)
• Betimol Use in Pregnancy & Breastfeeding
• Betimol Drug Interactions
• Betimol Support Group
• 0 Reviews for Betimol - Add your own review/rating

• Betimol Prescribing Information (FDA)


• Betimol Advanced Consumer (Micromedex) - Includes Dosage Information


• Betimol Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Timolol Ophthalmic Prescribing Information (FDA)


• Istalol Prescribing Information (FDA)


• Istalol Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Istalol Consumer Overview

Compare Betimol with other medications

• Glaucoma, Open Angle
• Intraocular Hypertension

Where can I get more information?

• Your pharmacist can provide more information about timolol ophthalmic.

See also: Betimol side effects (in more detail)